Case Report: Cholangiohepatitis in a dog

9 April 2018 – News

This case report describes the diagnostic approach for a 9-year-old female Yorkshire terrier, presented at consultation with anorexia, vomiting, and diarrhea. These clinical signs had been going on for 2 weeks. Hyperthermia, depression and weight loss were also noted on physical examination.

Blood tests showed some degree of dehydration, inflammation, liver damage, reduced hepatic function, and cholestasis. Ultrasonographic findings included marked gallbladder wall thickening and distension of the bile duct. A sample of bile was obtained through an eco-guided fine-needle aspiration and a liver biopsy was performed.

The sample was submitted for bacterial culture and revealed the presence of Clostridium sp. The biopsy showed inflammation, bile duct hyperplasia, and mild, multifocal, hepatocyte necrosis. It was concluded that an infectious cholangiohepatitis was causing the clinical signs and proceeded with medical treatment.

This condition is more common in cats than it is in dogs and presents with non-specific clinical signs. Performing the adequate complementary tests is key for an early diagnosis. New blood tests were performed two months after the dog’s treatment and came back within normal ranges.